Endothelial dysfunction and inflammation have been implicated in the pathophysiology of cerebral small vessel disease (SVD). However, whether they are causal, and if so which components of the ...

Three male mice of 3 months (3 m) and three male mice of 22 months (22 m) were used for mouse aorta isolation. Human umbilical vein endothelial cells (HUVECs) (20) were cultured in the endothelial ...

In the last 15 years, the introduction of endothelial keratoplasty (EK) procedures, where diseased corneal endothelium (CE) are selectively replaced, has significantly transformed the field of corneal ...

Close proximity and attachment of neutrophils to the endothelial lining in sepsis probably enable proteolytic enzymes to be released, which damage the endothelial surface. 20 Compensatory ...

Collective cell migration is defined as the coordinated movement of multiple cells that retain cell–cell contacts while coordinating their actin dynamics and intracellular signalling. Because ...

By applying the inferCNV algorithm, we evaluated copy number variability across cell subpopulations, using vascular endothelial cells as a reference ... Moreover, the identification of intercellular ...

Detecting danger is key to the survival and success of all species. Animal nervous and immune systems cooperate to optimize danger detection. Preceding studies have highlighted the benefits of ...