Investigators recommend a dose of 0.2 mg/mL losartan 6 times per day for patients with a current corneal epithelial defect. Topical losartan for the treatment of scarring corneal fibrosis mediated by ...

BACKGROUND/AIMS Autologous serum drops have been reported to be beneficial in keratoconjunctivitis sicca (KCS) and persistent epithelial defects (PED). A clinical pilot study was carried out to ...

Lufepirsen is under clinical development by Amber Ophthalmics and currently in Phase II for Persistent Corneal Epithelial Defects. According to GlobalData, Phase II drugs for Persistent Corneal ...

Eyes were further grouped according to Mackie's classification [24] into stage 1: neurotrophic keratopathy with punctate staining, vascularization, or scarring but no epithelial defect ...

On the left eye, the patient had conjunctival congestion and hyperemia, a central 2- × 2-mm corneal epithelial defect with deep stromal infiltration, endothelial plaque, moderate anterior chamber ...

Kala Pharmaceuticals Inc (NASDAQ:KALA)., a micro-cap biotech company valued at $40.13 million, has seen its stock reach a 52-week high, hitting an impressive $8.81. This peak reflects a significant ...

Centre de recherche du Centre hospitalier de l’Université de Montréal (CRCHUM), Montréal, Québec H2X 0A9, Canada ...

Reportedly, intestinal probiotics can affect the renewal of intestinal epithelial cells, and also make cell connections closer, increase the production of tight junction proteins and mucins, promote ...

These alterations led to dysfunction of the epithelial barrier and invasion of commensal bacteria into the mucosa. Conclusions A defect in ClC-3 may contribute to the pathogenesis of IBD by promoting ...

Following T cell commitment, developing T cells undergo multiple selection checkpoints by engaging with the extracellular matrix, and interacting with thymic epithelial cells (TECs) and other immune ...

With its acceptance by the NMPA, NVK002 is now under regulatory review across three major global markets: the United States, ...