If you're over the age of 60, you've likely seen headlines in the last couple of years warning against previous medical advice to take aspirin as a preventative measure against heart attack and ...

The best time for antithrombotic therapy is as early as possible after diagnosis, ideally in the early stage of the disease. We also elaborate on the possible mechanisms of long COVID thromboembolic ...

Peripherally induced Tregs express cyclooxygenase-2, secrete PGE 2, and elicit the immunosuppressive cAMP pathway in Teff as one tumor immune evasion mechanism. Moreover, a cAMP increase can also be ...

Copy number variants (CNVs) arise by homologous recombination (HR) between repeated sequences (recurrent CNVs) or by non-homologous recombination mechanisms that occur throughout the genome (non ...

As an additional means of meeting these targets, the Kyoto Protocol introduced three market-based mechanisms, thereby creating what is now known as the carbon market. Stimulate sustainable development ...

ORF3a, an accessory protein of SARS-CoV-2, mediates the transmembrane transport of water, leading to lysosome swelling. This function could, in principle, result in lysosome inactivation, a ...

MOHALI: Two former Punjab Police cops, both aged over 70, were on Tuesday awarded life sentence for the killing of an Army jawan and a farmer, falsely implicated in a murder case and accused of ...

ACS: Acute coronary syndrome; CV: Cardiovascular; MI: Myocardial infarction; PCI: Percutaneous coronary intervention; TIA: Transient ischemic attack.

HAMLET suppresses β-catenin-dependent transcription. The effects of HAMLET were ion channel-dependent, defining a new mechanism modulating β-catenin signalling and survival in colon cancer cells.

75 Sildenafil and tadalafil are reversible competitive inhibitors of the catalytic domain of PDE-5 involved in the hydrolysis of cGMP. Sildenafil was the first PDE-5 ... An improved understanding of ...