In humans, heart injury leads to the formation of scar tissue and cardiomyocyte hypertrophy ... connective-tissue scars in the absence of proliferation. These results provide an interesting model to ...

Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration. Cell. 2018 Mar 22;173 (1):104–116 Riham Abouleisa, Lindsey McNally, Abou bakr Mohamed Salama, Sally K.

As a part of the Regenerative Pharmacology Unit of the Drug Research Program, our group aims at discovering new ways to treat heart diseases by investigating the molecular mechanisms of cardiac ...

The study, titled Cross-Species Comparison Reveals Hmga1 Reduces H3K27me3 Levels to Promote Cardiomyocyte Proliferation and Cardiac Regeneration, was published in Nature Cardiovascular Research.