assemble focal adhesions and display tissue phenotypes characteristic of MECs interacting with a stiff matrix. Such observations underscore the importance of integrin signalling and Rho-dependent ...

Intercellular adhesion can be mediated by adherens junctions, tight junctions and desmosomes, whereas cells can interact with extracellular matrix molecules through focal adhesions. Differences in ...

We find that long-term mechanical compression triggers cell arrest in benign epithelial cells and enhances cancer cell migration in transitions correlated with cell shape, leading us to examine the ...

In senescent cells, these focal adhesions become abnormally large and strong. The researchers found that AP2A1 helps transport a protein called integrin β1 along stress fibers to build and maintain ...

In senescent cells, these focal adhesions become abnormally large and strong. The researchers found that AP2A1 helps transport a protein called integrin β1 along stress fibers to build and ...

MFGE8 was found to exert anti-fibrotic properties through integrin αvβ5 and focal adhesion kinase (FAK) in human intestinal myofibroblasts (HIMF), presenting a potential therapeutic pathway for ...

University of Maribor, Faculty of Mechanical Engineering, Laboratory for Characterisation and Processing of Polymers, Smetanova ulica17, 2000 Maribor, Slovenia Members of the European Polysaccharide ...

Focal dystonia is a neurological disorder involving involuntary spasms and cramping in muscles, such as the hands and fingers. It can result from overuse and tends to affect musicians, golfers, or ...

and proline-rich tyrosine kinase-2 (Pyk2), the two members of the focal adhesion kinase family of non-receptor protein tyrosine kinases. FAK and Pyk2 integrate signals from integrin and growth factor ...

During CP+ 2025, Sony unveiled a new wide angle prime lens – and the new optic is both shorter and more affordable than the brand’s next closest lens. The Sony 16mm f/1.8 G is an ultra-wide compact ...

School of Life Sciences, University of Warwick, Coventry CV4 7AL, U.K.