Methods: Caco-2 mature monolayers grown on Transwell membranes were challenged with apical or basolateral LPS. After stimulations, the enterocyte-like monolayers were transferred in co-culture with ...

After pathogen clearance, macrophages shift phenotype to promote wound repair. Shifts in phenotypes are termed “polarization” and have historically been modeled by exposure to soluble mediators such ...

The combination of LPS, MLMs, and inflammatory cytokines may increase intestinal permeability, allowing the excessive release of commensal bacterial products. This promotes M2 macrophage ...

ABSTRACT: The concept of neuroimmune interactions has shown significant advancements over the years. Modern research has revealed many areas of connection between fields, which were previously viewed ...

In a recent study published in Science Advances, researchers led by Prof. Li Xinjian from the Institute of Biophysics of the ...

Phagocytosis is a fundamental mechanism used by the body to resist pathogens and restore physiological homeostasis. Herein, to identify small molecules with anti-inflammatory properties via ...

This important study reveals that disrupting fatty acid metabolism in macrophages significantly restricts the growth of Mycobacterium tuberculosis, showing that impaired lipid processing triggers ...

SEE ALSO: Get the latest forecast from the Storm Alert Team All LPS activities are also canceled, the district said. LPS said it would continue to monitor the conditions for Thursday.

This study provides a comprehensive exploration of the role of IL-1β signaling during development of lung injury induced by a combination of underlying inflammation and mechanical ventilation. The ...

When exposed to various stimuli, monocytes/macrophages are recruited to and retained within the local tissue microenvironment, where they can activate and display either proinflammatory or ...