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靶向脂筏中的hERG1/β1整合素复合物可增强他汀类药物在胰腺癌中的 ...
脂质筏(LRs)作为细胞膜的重要组织者,在细胞信号传导中发挥关键作用。其富含胆固醇、鞘脂等成分,为多种信号分子提供了特定的微环境,使生化反应更高效、精准。在癌症发展进程中,LRs 参与调控多个关键环节,如细胞增殖、迁移和侵袭等,是极具潜力的抗癌药物靶点。
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