The transition of MDMs from M1 to M2 phenotype was evaluated through gene expression and protein synthesis of M2 macrophage markers, namely scavenger receptors (CD163 and CD204), and mannose ...

Colorectal cancer (CRC) is the third most common malignancy and the second leading cause of cancer-related deaths worldwide.

Macrophages are activated mainly in two ways and resulted in three phenotypes: classically activated macrophages (M1), alternatively activated macrophages (M2). The most characteristic of these cells ...

The interaction between the microenvironment and cancer cells remains to be further elucidated. In this study, we characterized the prognostic value of P311 in PDAC and aimed to examine the ...

Interestingly, this study noted an increase in the proportion of M1 macrophages and a decrease in M2 macrophages in CRC, contradicting the M1/M2 polarization theory. Functional analyses suggests ...

1 Division of Infectious Diseases, Department of Pediatrics, Washington School of Medicine in St. Louis, St. Louis, MO, United States 2 Division of Immunobiology, Department of Pathology and ...

State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), ChemBioMed Interdisciplinary Research Center, ...

New tumor markers such as Tumor M2-PK must first prove their equality or superiority before they can be adopted as a new option. As is well known for other tumor markers such as CA 19-9 ...

Determination of M2-PK in the plasma in the surveillance of pancreatic, cholangiocellular, esophageal, colorectal or gastric carcinoma seems at least equal to the established tumor markers.

BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...