M cells, or microfold cells, play a crucial role in the immune system, particularly in mucosal immunity. These specialized epithelial cells are primarily found in the gut-associated lymphoid ...

Figure 1. Schematic representation of specialized follicle-associated epithelium in the intestinal lamina propria. Microfold (M) cells sample different types of antigens, including microbe-associated ...

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.

Salmonellae use two type III secretion systems (T3SSs) to deliver bacterial virulence proteins, called effectors, directly into host cells. The T3SS that is encoded on Salmonella pathogenicity ...

Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells do not express ...

RANKL has essential roles in the formation of mammary gland and lymphoid organs by stimulating proliferation or differentiation of epithelial cells and stroma cells via NF-κB-mediated processes.

The system they developed may facilitate the transportation of large therapeutic loads into cells. This opens up a new way for the targeted administration of medication and other therapeutic ...

In 2009 a team of biophysicists led by Anthony A. Hyman of the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, Germany, were studying specklelike structures called P ...

Detecting danger is key to the survival and success of all species. Animal nervous and immune systems cooperate to optimize danger detection. Preceding studies have highlighted the benefits of ...

Many cells in multicellular organisms are specialised. They have specific roles in the organism of which they are part. Their structure is adapted to their function. They are often grouped ...