Northwestern Medicine investigators have uncovered new insights into how intercellular "glue" functions to enable interactions between cells, as detailed in a study published in Nature Communications.
研究人员通过分析 TCGA 数据库,发现 miR-101-3p 在肝癌组织中的表达低于正常组织,且其低表达与肝癌患者的不良预后相关。在临床样本和细胞系中也证实了这一点,像 QGY7701 和 HepG2 这些肝癌细胞系中 miR-101-3p 的表达明显低于正常细胞。
For T-cadherin overexpression, we employed the pcDNA3.1-DsRed-Tcad plasmid encoding human CDH13 cDNA, a kind gift from the Laboratory of Cellular Engineering led by T.N. Vlasik, at the Federal State ...
Subgroup analysis suggests that ECFC from patients with COPD on inhaled corticosteroids (ICS) (n=14; eight on ICS) exhibited significantly reduced senescence (Senescence-associated-beta galactosidase ...
PRAGUE, Czech Republic and LONDON, UK I March 03, 2025 I SOTIO Biotech, a clinical-stage biopharmaceutical company owned by PPF Group, today presented the first preclinical data on SOT109, a novel ...
targeting cadherin-17 (CDH17). The data highlight SOT109's promising activity and tolerability profile across multiple disease models, reinforcing its potential to become a best-in-class ...
为探究可溶性 E - 钙粘蛋白(sE-cadherin)在 ALI/ARDS 中的作用,广州医科大学附属第一医院研究人员开展相关研究,发现 sE-cadherin 通过 VEGF/VEGFR2 通路促进肺炎症,为 ALI/ARDS 治疗提供新方向。 急性肺损伤(ALI)及其更严重的急性呼吸窘迫综合征(ARDS),就像潜伏在 ...
You’re searching through the classified ads, and you come across a car you like. But in the listing, it states the car is ‘Cat S’ or ‘Cat N’. What does that mean exactly, and why is it important? In ...
N-Cadherin, an adherens junction protein, is identified as a key regulator of cardiomyocyte (CM) proliferation and renewal. Its expression decreases with age but increases in neonatal mice after ...
03 3.缺氧诱导人非小细胞肺癌细胞EMT和干性缺氧细胞呈间质化改变,HIF-1a、Snail、N-cadherin和Vimentin表达上调,而E-cadherin表达下调。缺氧细胞球体形成 ...