IFN-γ secretion was analyzed on electronically gated NK cells, NKT cells and T cells by flow cytometry. Wiley, S.R. et al. Identification and characterization of a new member of the TNF family ...

finding a predominant expression in monocytes and myeloid-derived suppressor cells (MDSCs), with a marked reduction in CD4+ and CD8+ T cells, as well as in natural killer T (NKT) cells. Patients with ...

Conclusions: Our study shows clear differences in the intrahepatic expression of ICMs on NK cells and T cells in chronic HBV patients depending on their clinical stage. Hepatitis B is one of the most ...

NK and NKT cells DCs promote induction of adaptive responses Immune activation mediated by DCs, NK cells and NKT cells enhances HIV replication A. Development of microbicides and passive ...

The investigators tested these CAR-NK cells alone in 18 patients and for the remainder in combination with rituximab, a monoclonal antibody that helps further target the CAR-NK cells to lymphoma ...

Conversely, although CC OMVs induced less overall splenocyte proliferation, the absolute counts of lymphocytes, including NK cells, CD4+ T cells, CD8+ T cells, and NKT cells, were the highest (Figure ...

Gilead Sciences' cell therapy Kite Pharma has bulked up its position in natural killer (NK) cell therapies, pledging up to $2.3 billion for a partnership with Shoreline Bioscience focusing on off ...

To create one of the most advanced immunotherapies in cancer, CAR-T cell therapies, scientists engineer immune T cells to carry a synthetic protein on their surfaces. This protein, called the ...

Antigen-specific T helper and NKT cells, homeostatically restrained by Treg cells, contribute to intestinal inflammation and their influx can be therapeutically targeted. Work in the Kaser lab is ...

Jan. 28, 2025 — A team of stem cell scientists have successfully used embryonic stem cell engineering to create a bi-paternal mouse -- a mouse with two male parents -- that lived until adulthood.