Copanlisib in combination with immune checkpoint inhibitors demonstrated synergy and favorable antitumor immune responses in preclinical models. This study evaluated copanlisib plus nivolumab in ...

School of Chemical Engineering and Technology, State Key Laboratory of Synthetic Biology, Frontiers Science Center for Synthetic Biology (Ministry of Education), Tianjin University, Tianjin, P. R.

Among the general data from the CheckMate 649 trial (NCT02872116) of nivolumab plus chemotherapy, he touched on the continuing debate of using combined positive score (CPS) of PD-L1 as a cut-off, as ...

The FDA is conducting a priority review of nivolumab plus ipilimumab for the first-line treatment of patients with unresectable or metastatic MSI-H/dMMR colorectal cancer. The FDA has accepted a ...

Finally, we reasoned that certain resistance plasmids should themselves expedite re-seeding-transfer-invasion cycles within the infected host. In particular, this should pertain to plasmid-encoded ...

Plasmid-mediated dissemination of antibiotic resistance among fecal Enterobacteriaceae in natural ecosystems may contribute to the persistence of antibiotic resistance genes in anthropogenically ...