Polyphosphate (polyP) exists in all life forms; however, its biological functions in metazoans are understudied. Here, we explored Drosophila as the first genetic model to explore polyP biology in ...

Site-specific endonucleases that exclusively cut single-stranded DNA have hitherto never been described and constitute a barrier to the development of ssDNA-based technologies. Here the authors ...

The tumor cells had round to convoluted nuclei, dense chromatin, inconspicuous nucleoli and scant basophilic cytoplasm. Brisk mitotic activity was noted. A provisional morphological diagnosis of small ...

Most migrated to the nucleolus, as expected, but one protein steadfastly refused. Instead, it formed nuclear dots that were much smaller than the large and obvious nucleoli. I was really worried about ...

A long-standing question has been to understand which of the many ribosomal RNA clusters are expressed and how they are regulated. Here the authors characterize a new, noncoding RNA SNUL-1 and propose ...

Nucleoli are subcellular compartments where transcription and maturation of pre-ribosomal RNAs occur. While the transcription of ribosomal RNAs is common to all living cells, the presence and ...