Research into organ of Corti hair-cell regeneration is ongoing and may offer recovery of hearing in the next century. Dr. Murphy is a Resident in the Department of Otolaryngology/Head and Neck ...
记者从中国科学院脑科学与智能技术卓越创新中心(神经科学研究所)获悉,该中心刘志勇研究组通过研究揭示了锌指转录因子Casz1在听觉毛细胞中的作用,并解析了Casz1发挥功能的分子机制,为探索基因操纵修复听觉损伤提供了新的思路和靶点。该科研成果北京时间1 ...
They incorporate into the lateral wall of the cochlea starting at around E15.5 following a basal to apical gradient reminiscent of the differentiation of hair cells in the organ of Corti. Intermediate ...
Active outer hair cells deformed the organ of Corti like a peristaltic tube to generate apically streaming flows along the tunnel of Corti and basally streaming flows along the scala tympani. Our ...
However, the ectopic hair cells seems to be generated from supporting cell trans-differentiation, and the intricate mosaic of the organ of Corti is altered (the extra row of IHCs seems to be ...
Mouse models with overproduction of hair cells have hearing loss, suggesting that the location, hair cell number and general morphology and architecture of the organ of Corti are important ...
The role of the outer hair cells in hearing is both sensory and mechanical. When the organ of Corti begins to vibrate in response to the incoming sound, each hair cell will sense the vibration through ...
The electrical and chemical gradients between the endolymph and perilymph function to power the cochlea and are maintained by the stria vascularis. The organ of Corti runs longitudinally along the ...
对于广大听障患者而言,Casz1的研究成果意味着更多的治疗选择和希望。根据相关数据,我国每年新增听力障碍患者数以百万计,如何改善这一现状是亟需解决的社会问题。Casz1在听觉毛细胞中的作用,有望通过基因治疗的手段,促进耳蜗毛细胞的再生和纤毛功能的恢复 ...
Organ transplantation is the most effective therapy for patients with end-stage disease. Preservation solutions and techniques are crucial for donor organ quality, which is directly related to ...
Argentine Libertarian Congressman Javier Milei said he was in favor of the sale of human organs or transplants because “it is just another market.” After stirring controversies among ...
"Recycling" an already transplanted organ could help save lives, but the procedure comes with additional risks, physicians say. When you purchase through links on our site, we may earn an ...