Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea ...

Liquid- and solid-phase synthesis approaches were applied to aptamer modification according to modification positions. To maximize the chemical diversity, 2′-hydroxyl modification, base modification, ...

Biosynthesis can be exploited for chemical synthesis in vitro or in cells like Escherichia coli by combining substrates with enzymes using recombinant methods. The introduction of fluoroalkyl ...