The original form of ketamine, formally known as "racemic" ketamine, is composed of two mirror-image molecules or enantiomers, known as S(+)-ketamine and R(–)-ketamine. S(+) and R(–) forms of ...

In recent years, there has been particular interest in the antidepressant effects of ketamine in patients with TRD. Ketamine is a racemic mixture of two enantiomers, R- and S-ketamine, with the latter ...

The mechanism of action underlying ketamine’s rapid antidepressant effects in patients with depression, both suffering from major depressive disorder (MDD) and bipolar disorder (BD), including ...

It develops AWKN-001, a novel medication-assisted treatments (MAT) consisting of racemic ketamine, delivered intravenously, and manualized relapse prevention cognitive behavioural therapy (CBT ...

The recent acquisitions by pharmaceutical giants Johnson & Johnson and Bristol Myers Squibb, worth a combined $28billion, ...

an intranasal formulation of racemic ketamine. Vertex's gene-editing therapy for sickle cell disease, Casgevy, has been given the nod for use by the NHS in England after an earlier rejection.

Jeff Winograd, who's lived with depression for more than 25 years, says ketamine treatment saved his life. Jeff Winograd couldn’t get off his couch. He’d hit rock bottom with the depression he ...

In interviews, Musk has mentioned using doctor-prescribed ketamine to alleviate periods of depression. He believes that managing his mental health is beneficial not only for his well-being but also ...

A phase III evaluation, the largest of its kind to date for racemic ketamine-assisted therapy in AUD, is underway. The study, conducted at eight National Health Service (NHS) sites across the UK ...