In recent years, there has been particular interest in the antidepressant effects of ketamine in patients with TRD. Ketamine is a racemic mixture of two enantiomers, R- and S-ketamine, with the latter ...

Although natural sources of compounds that contain the oxazolidin-2-one nucleus are very rare, 5 Kakeya et al. 6 were able to isolate a novel compound belonging to this class, ...