虽然这项研究不会直接导致用于治疗感染或疾病的新疗法,但它将使研究人员更好地了解免疫系统遵循的规则。研究人员如今更清楚地知道,在开发治疗方案时,应该拉动哪些杠杆来做出更有效的选择,以防止T细胞遵循功能衰竭的路线,并推动它们继续进行良好的斗争。( 生物谷 Bioon.com) ...
Immune dysfunction during chronic infections and cancer leads to disease progression due to T cell exhaustion. In this process, CD8 + T cells fail to form functional memory. T cell exhaustion results ...
Virax Biolabs Group Limited ("Virax" or the "Company") (Nasdaq: VRAX), an innovative biotechnology company focused on the detection of immune responses and diagnosis of viral diseases, today announced ...
Expression of tissue factor (TF) in penile squamous cell carcinoma (PSCC) and enrichment in HPV-negative cases. This is an ASCO Meeting Abstract from the 2025 ASCO Genitourinary Cancers Symposium.
Basophils trigger a cytokine cascade that improves antitumor immunity in mice, offering potential targets for cancer immunotherapy.
The researchers showed that removing Asxl1 prevented T-cell exhaustion, enabling long-term immune responses. "We found Asxl1 ...
The study showed that T-cells expressing the cell receptor CD38 were more susceptible to exhaustion. Using an anti-CD38 antibody, the research team was able to block CD38 and overcome T-cell ...
Biosciences announced the presentation of preclinical data investigating the potential of co-administration of deoxyribonuclease ...