These intracellular signaling pathways, also called signal transduction cascades, typically amplify the message, producing multiple intracellular signals for every one receptor that is bound.

Mapping the key signaling molecules in biochemical pathways will be central to future drug discovery efforts. Signal transduction describes the process of conversion of external signals ...

Davis, University of Massachusetts Medical School, Howard Hughes Medical Institute. The signal transduction pathways of mitogen-activated protein (MAP) kinases have been actively studied for some time ...

The main goal of our laboratory is the identification and characterization of signal transduction pathways that cause the dysregulation of growth and inhibition of apoptosis that characterize advanced ...

Members of the program engage in research aimed at obtaining a mechanistic understanding of signal transduction and cellular regulation, which includes cellular signaling pathways and downstream ...

Saltiel, department of signal transduction, Parke-Davis, Ann Arbor, Mich. The chemical signals triggering cellular growth resemble multiple pathways more closely than a single trail. Consequently, ...