Correspondence to Dr John Ferguson, Clinical Research Facility, National University of Ireland Galway, Galway, Ireland; john.ferguson{at}nuigalway.ie Commonly accepted statistical advice dictates that ...

Correspondence to Georgia C Richards, Center for Evidence-Based Medicine, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford OX2 6GG ...

Correspondence to Dr Kerry Dwan, Centre for Reviews and Dissemination, University of York, York, UK; Kerry.dwan{at}york.ac.uk A systematic review identifies, appraises and synthesises all the ...

Correspondence to Sir Iain Chalmers, James Lind Initiative, Summertown Pavilion, Middle Way, Oxford OX2 7LG, UK; ichalmers{at}jameslind.net We are surrounded by maelstroms of claims about the effects ...

Correspondence to Dr Mohammad Hassan Murad, Evidence-based Practice Center, Mayo Clinic, Rochester, MN 55905, USA; murad.mohammad{at}mayo.edu When decision makers make a recommendation based on ...

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Correspondence to: Dr Cuilin Zhang, Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National ...

Globally, drug regulators have approved statins for the prevention of cardiovascular disease (CVD), although their use in primary prevention has been controversial. A highly publicised debate has ...

Participants 150 women (18–45 years of age) with PMS or premenstrual dysphoric disorder. Intervention Random assignment (1:1:1) to treatment as usual (TAU), OLP without treatment rationale (OLP–), or ...

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Developing a clinical practice guideline (CPG) is expensive and time-consuming and therefore often unrealistic in settings with limited funding or resources. Although CPGs form the cornerstone of ...

Objective To determine, for people seeking a date online, what activities and behaviours have an effect on the chances of converting electronic communication into a face-to-face meeting. Methods ...