Significance In the past, there has been a paucity of clinical and demographic information on inflammatory bowel disease in the Philippines. At the UERMMMMC, there was a growing trend for IBD ...

2 Department of Gastroenterology, Gloucestershire Hospitals NHS Foundation Trust, Cheltenham General Hospital, Cheltenham, UK 3 Department of Gastroenterology, Gloucestershire Hospitals NHS Foundation ...

Background and aim: The importance of the hepatocyte ploidisation pattern to the control of cell proliferation and differentiation has been well established. However, there are no data that have ...

Background Chicoric acid (CA), a hydroxycinnamic acid, has been reported to possess anti-inflammation activities. However, the specific mechanisms by which CA influences dextran sulfate sodium ...

Objective An international meeting was organised to develop consensus on (1) the landmarks to define the gastro-oesophageal junction (GOJ), (2) the occurrence and pathophysiological significance of ...

Objective To determine whether new users of proton pump inhibitors (PPIs) are at an increased risk of gastric cancer compared with new users of histamine-2 receptor antagonists (H2RAs). Design Using ...

BACKGROUND/AIMS Vascular endothelial growth factor (VEGF) plays a key role in regulation of tumour associated angiogenesis. In the current study we analysed expression of VEGF and its receptors in ...

Department of General Surgery, Buckinghamshire Hospitals NHS Trust, Aylesbury, UK Correspondence to: MrK Gurusamy Department of General Surgery, Buckinghamshire Hospitals NHS Trust, 5 North Drive, ...

Objective Tumour heterogeneity represents a major obstacle to accurate diagnosis and treatment in gastric adenocarcinoma (GA). Here, we report a systematic transcriptional atlas to delineate molecular ...

Introduction Survival from oesophageal cancer remains poor, even across high-income countries. Ongoing changes in the epidemiology of the disease highlight the need for survival assessments by its two ...

Correspondence to Professor Xian-Jun Yu, Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, China; yuxianjun88{at}hotmail.com Design We combined molecular ...

Objective Patients with increased PD-L1 + host cells in tumours are more potent to benefit from antiprogrammed death-1/programmed death ligand-1 (PD-L1) treatment, but the underlying mechanism is ...