Disinfectants induce oxidative damage in bacteria, but a single mutation triggers the expression of genes that help the ...

Encasing CRISPR tools in oil droplets offers a fast-track approach to conducting extensive genetic screens in animals.

Researchers at Cellectis leveraged gene editing to create a CAR T cell that acts in an IF/THEN system. Traditional methods to develop CAR T cells that use the patient’s cells introduce challenges ...

Genetic medicines could treat certain diseases, however, the current delivery systems available—viral vectors and lipid nanoparticles (LNPs)—pose unique challenges for gene therapy applications. For ...

A single gene controls earwax and body odor, shaping one’s unique scent through microbes. In 2006, scientists identified the culprit: the ATP binding cassette subfamily C member 11 ( ABCC11) gene. 1 A ...

Both Cas9 and Cas12a cleave DNA, but they differ in how they cut the molecule.

Genetic alterations may help mosquitoes adjust to climate change, shifting the distribution of mosquito-borne disease in a ...

Scientists increase the efficiency and scalability of their single-cell RNA sequencing experiments by using innovative barcoding technology.

In the 20th century, animals such as mules and ligers that had parents of different species were considered biological flukes, but genetic sequencing is beginning to unravel the critical role of ...

Plasmodium falciparum has shown an ability to evade everything we throw at it, most recently artemisinin-based combination therapies, today’s front-line treatment.

Uniform protein labeling in intact tissues is a challenge. An approach that allows antibodies to seep within organs could ...

Editor's Note: On Feb. 1, 1944, the Journal of Experimental Medicine published a scientific paper entitled "Studies on the chemical nature of the substance inducing transformation of pneumococcal ...