This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights ...

This study provides compelling evidence that kinesin's stepping mechanism is governed by strain-induced conformational changes in its nucleotide-binding pockets. Using pre-steady state kinetics and ...

For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event ...

Scientists have provided the most detailed account yet of the earliest stages of DNA replication, an essential process for ...

"This achievement will promote further understanding of the motility mechanism of how the energy of ATP hydrolysis is converted into gliding motility, and how these motors of Mycoplasma mobile are ...

"This achievement will promote further understanding of the motility mechanism of how the energy of ATP hydrolysis is converted into gliding motility, and how these motors of Mycoplasma mobile are ...

Edited by Donald Ort, University of Illinois at Urbana Champaign, Urbana, IL; received December 10, 2024; accepted January 28, 2025 ...

ATP burning, or hydrolysis, functions like the spring in a mouse trap, snapping the helicase forward and pulling the DNA strands apart," said De Biasio. Among the many discoveries made by the ...