2 Most will agree that these goals are probably achieved best by normalizing secretion of growth hormone and insulin-like growth factor 1 (IGF-1) and that the sequelae of acromegaly are serious ...

Acromegaly is due to hypersecretion of growth hormone and insulin-like growth factor I (IGF-I). The aim of treatment is to limit this excess secretion and to reduce morbidity and mortality.

Causes: Acromegaly occurs when the pituitary gland, a small hormone-making structure in the brain, produces too much growth hormone for a long period of time. This hormone normally regulates the ...

Endocrinology specialist Dr Preethi Dissanayake discusses this uncommon presentation, in the latest in our series on conditions that GPs may only encounter once in their career Acromegaly is a rare ...

But as the years went on, he began to notice his body changing in unusual ways: His head grew so much that he needed a larger helmet, and his hands became so big he had to have his wedding ring ...

Acromegaly (Greek-enlargements of the extremities) is a hormonal disorder resulting from excessive production of the growth hormone by the pituitary gland after puberty, often referred as gigantism.

The following is a summary of “Paradoxical GH response at OGTT does not predict Pasireotide efficacy but matters for glucose metabolism,” published in the January 2025 issue of Endocrinology by Occhi ...

Acromegaly Overview Acromegaly is a rare, slowly progressive, acquired disorder that affects adults. The pituitary gland produces too much growth hormone (GH). The pituitary gland is a small gland ...

Second Lead Pipeline Program Announced: MAR002 for the Treatment of Acromegaly MAR002 is a potential first-in-class anti-growth hormone receptor (GHR) antibody being developed for acromegaly.