C&EN1 个月
Synthesis and SAR Studies of Acyl-Thiourea Platinum(II) Complexes Yield Analogs with Dual ...
Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa Department of Biochemistry, Genetics and Microbiology, Institute for Sustainable Malaria Control, University of Pretoria ...
C&EN1 个月
Insights into Free Drug Release from Efficacious N-Acyl O-Aminophenol Duocarmycin Prodrugs
Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, United States ...
eLife4 年
Cooperative enzymatic control of N-acyl amino acids by PM20D1 and FAAH
The N-acyl amino acids are a family of bioactive lipids with pleiotropic physiologic functions, including in energy homeostasis. Their endogenous levels are regulated by an extracellular mammalian ...
eLife8 年
The mitochondrial acyl carrier protein (ACP) coordinates mitochondrial fatty acid synthesis ...
Mitochondrial fatty acid synthesis (FASII) and iron sulfur cluster (FeS) biogenesis are both vital biosynthetic processes within mitochondria. In this study, we demonstrate that the mitochondrial acyl ...