This mini-review summarizes the current evidence for the role of macrophage activation and polarization in inflammation and immune response pertinent to interstitial lung disease, specifically ...

In addition, type I IFNs affect macrophage functions by enhancing their tumoricidal and phagocytic capacities and shaping a tumor-suppressive tumor microenvironment (TME), which is characterized by ...

Further analysis revealed that hypoxic CD71+ neutrophils expressed an additional gene, ARG1, that caused the immunosuppressive effect. Without ARG1, even hypoxic CD71+ neutrophils did not suppress ...

The hypoxic CD71 + neutrophils had come to acquire ARG1 expression and its immunosuppressive effects, but researchers did not yet know how. Dr. Veglia and team suspected an interplay between ...

This cover highlights the article Multimodal mechanisms of human centriole engagement and disengagement by Kei K. Ito, Shoji Hata, Daiju Kitagawa and colleagues. The cover image depicts the centriole ...

Department of Physiology, State Key Laboratory of Common Mechanism Research for Major Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Basic Medical ...

Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02115, United States Alnylam ...

Division of Evolution, Infection & Genomic Sciences, University of Manchester, Manchester M13 9PL, U.K. Division of Evolution, Infection & Genomic Sciences ...