This cover highlights the article Multimodal mechanisms of human centriole engagement and disengagement by Kei K. Ito, Shoji Hata, Daiju Kitagawa and colleagues. The cover image depicts the centriole ...

Males with pulmonary arterial hypertension (PAH) have more proinflammatory macrophages — a type of immune cell — in the lungs than do females with the disease, a study suggests. Researchers identified ...

Io Biotech Aps has presented preclinical data regarding their Arg1-derived peptide cancer vaccine IO-112 as a potential immunotherapeutic that would allow controlling the tumor microenvironment.

This important study reveals that disrupting fatty acid metabolism in macrophages significantly restricts the growth of Mycobacterium tuberculosis, showing that impaired lipid processing triggers ...

This study provides useful information by identifying the cell type (macrophages) in synovial tissues involved in the pathogenesis of post-traumatic osteoarthritis (OA) and clarifying distinct ...

When exposed to various stimuli, monocytes/macrophages are recruited to and retained within the local tissue microenvironment, where they can activate and display either proinflammatory or ...

Furthermore, DKK1 potentiated IL-13-mediated macrophage polarization and activation. The co-inhibition of JNK and STAT6 markedly decreased gene expressions relevant to inflammation and fibrosis by ...

real-time RT-PCR was performed to detect mRNA expressions of M2 macrophage markers. AS1517499 treatment suppressed mRNA expression abundance of Arg1, MRC1, Fizz1, and CCL17 in obstructed kidneys ...