More than half of patients with ischemic stroke experience futile reperfusion, increasing the risk of death and disabilities despite a successful recanalization. The reason behind this is debated, and ...

Macrophages represent one of the most prevalent cells in the colorectal cancer microenvironment and play a pivotal role in maintaining intestinal health and the development of colitis-associated colon ...

This cover highlights the article Multimodal mechanisms of human centriole engagement and disengagement by Kei K. Ito, Shoji Hata, Daiju Kitagawa and colleagues. The cover image depicts the centriole ...

In addition, type I IFNs affect macrophage functions by enhancing their tumoricidal and phagocytic capacities and shaping a tumor-suppressive tumor microenvironment (TME), which is characterized by ...

Further analysis revealed that hypoxic CD71+ neutrophils expressed an additional gene, ARG1, that caused the immunosuppressive effect. Without ARG1, even hypoxic CD71+ neutrophils did not suppress ...