近年来，随着蛋白质组学技术的飞速发展，科研人员逐渐揭开了蛋白质翻译后修饰（PTM）在疾病发生发展中的重要作用。其中棕榈酰化（S-palmitoylation）作为一种重要的脂质修饰方式，逐渐成为研究热点。棕榈酰化通过在蛋白质的半胱氨酸残基上添加棕榈酸 ...

Atherosclerosis involves multiple processes including endothelial dysfunction, inflammation, vascular proliferation and matrix alteration. Vascular proliferation contributes to the pathobiology of ...

A key process in atherosclerosis is the endothelial-to-mesenchymal transition (EndMT), which involves the transformation of endothelial cells into mesenchymal cells, contributing to plaque ...

A key process in atherosclerosis is the endothelial-to-mesenchymal transition (EndMT), which involves the transformation of endothelial cells into mesenchymal cells, contributing to plaque ...

Atherosclerosis, or the buildup of plaque in the arteries, develops when low-density lipoprotein cholesterol (LDL-C) enters the blood vessel walls through dysfunctional endothelial cells (EC ...

Importantly, however, most of the data pointing to the role of autoimmunity in atherosclerosis comes from studies in transgenic mice. Human atherosclerosis is a complex disorder with a complex ...

Human papillomavirus appears to increase risk for cardiovascular disease and coronary artery disease, according to a ...

Atherosclerosis is a chronic, systemic, inflammatory and metabolic disease and pathologic process characterized by the accumulation of cholesterol and calcium plaque within the arterial wall.

Atherosclerosis is the buildup of plaque — a combination of cholesterol, fat, calcium, and blood elements — on and inside the walls of your arteries. Your arteries are the blood vessels that ...

Laminar shear stress due to blood flow is a principal regulator of systemic endothelial cell gene expression, morphology, and the production of soluble mediators. Its importance is highlighted by ...