Background/aims To study human corneal endothelial cells (HCECs) cultured in vitro with human serum (HS) supplemented media (HS-SM) compared with HCEC cultured in fetal bovine serum (FBS) supplemented ...

Research is underway to develop alternative treatments for corneal endothelial diseases, which are less dependent on the availability of allogeneic tissues – regenerative medicine and cell-based ...

This structural knowledge can inform the development of targeted therapies aimed at restoring the function of the mutated protein. Corneal Endothelium: A layer of cells on the inner surface of the ...

Vice versa, activated or dysfuntional endothelial cells may also affect the function of other cell types in the heart, including myocytes and non-myocytes. However, these mechanisms fail to stimulate ...

Intracameral placement, where the tube is inserted into the anterior chamber, poses a higher risk of endothelial cell damage due to direct contact between the tube and the corneal endothelium, which ...

Mesenchymal stromal cell (MSC) metabolism plays a crucial role in the surrounding microenvironment in both normal physiology and pathological conditions. While MSCs predominantly utilize glycolysis in ...

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The possible involvement of other cellular components in viral entry mechanisms remains unknown. Vimentin is expressed in human endothelial cells, binds to SARS-CoV-2-spike, and expedites SARS-CoV-2 ...