HDAC6 is upregulated in corneal diseases and causes ENKD1 deacetylation at lysine 98. Deacetylation of ENKD1 blocks its ...

Abstract: Segmenting corneal endothelial cells in conditions like Fuchs endothelial dystrophy (FED) is challenging due to guttae obscuring cell details and complicating imaging. This is further ...

The corneal endothelium showed a beaten bronze appearance without corneal edema (Figure 1b). The left fundus showed significant retinal venous tortuosity with an otherwise normal retina and a ...

using only donor Descemet's membrane with endothelium. However, early adoption by corneal surgeons has been limited (illustrated by graft registry reports: 0.7% all corneal transplants in the USA; 0.4 ...

Mount Sinai researchers identified stem cell populations and mechanisms sustaining adult meibomian glands, crucial for ocular health. The hedgehog (Hh) signaling pathway is vital for meibomian gland ...

The RESTORE VISION scientific team has identified seven rare ocular conditions that impact the cornea and the rest of the ocular surface. "With a comprehensive approach, we aim to restore the ...

It may also be critical in the development of lipid-rich, unstable plaques. Mechanisms have been controversial but recent evidence suggests that caveolar transcytosis across endothelial cells is the ...

AKC: Allergic keratoconjunctivitis; PAC: Perennial allergic conjunctivitis; SAC: Seasonal allergic conjunctivitis; SPK: Superficial punctuate keratitis; VKC: Vernal ...

The characteristic pain crises and organ failure seen in sickle cell disease results from the abnormal red blood cells adhesion to the endothelium of small vessels and subsequent blood flow cessation.