HDAC6 is upregulated in corneal diseases and causes ENKD1 deacetylation at lysine 98. Deacetylation of ENKD1 blocks its ...

Signal12 Pharmaceuticals has aligned with the FDA on its phase 3 clinical trial strategy for Pro-ocular, a novel drop-free ...

Visual analog scale symptom scores, corneal sensitivity, Schirmer I test value, tear film break-up time (TBUT), tear evaporation rate and ocular surface vital staining scores were recorded at ...

Results also showed significant improvements in corneal staining and tear production, with effects observed as early as week 4 and maintained through week 12. Patients reported reduced reliance on ...

Michelle Hessen, OD, discusses how cyclosporine ophthalmic solution 0.09% is safe to use in patients with dry eye, as well as where future research should turn.

Ocular surface disease parameters were also assessed. Corneal fluorescein staining improved in 52.6% of the patients and worsened in 10.5%. Conjunctival hyperaemia decreased in 63.3% of patients ...