Multiple sclerosis (MS) is a chronic, neurodegenerative autoimmune disease targeting the myelin sheath of primarily the central nervous system (CNS). With an estimated 2.8 million cases in 2020, the ...

Damage to myelin, the protective sheath surrounding nerve fibers, impairs the brain's ability to transmit signals efficiently ...

The immune system, a complex interactive network of many different immune cells, mediators, and cellular mechanisms, is highly dynamic in the response to changes in the tissue environment and plays a ...

Objective Liver injury impacts hepatic inflammation in part via Toll-like receptor (TLR) signalling. Triggering receptor expressed on myeloid cells 2 (TREM-2) modulates TLR4-mediated inflammation in ...

Researchers don’t yet fully understand what causes multiple sclerosis (MS) but believe it may develop from a combination of genetic and environmental factors. Identifying these factors can help ...