This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights ...

Scientists have provided the most detailed account yet of the earliest stages of DNA replication, an essential process for ...

Researchers at the Center for Embryology and Healthy Development (CRESCO) aim to find out why so many early embryos fail in ...

For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event ...

DNA replication is an essential nuclear process for genome stability maintenance. Physical barriers and difficult-to-replicate regions hinder replication fork progression and threaten the fidelity of ...

While scientists have long known the importance of helicase in DNA replication, "they did not know how DNA, helicases and ATP work together in a coordinated cycle to drive DNA unwinding," De ...

Using cutting-edge cryo-electron microscopy, scientists at the University of Leicester have captured the first detailed “molecular movie” showing DNA being unzipped at the atomic level. The movie ...

MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer.

The discovery, published in the peer-reviewed journal Nature, is stated to have far-reaching implications, helping us to ...

Scientists have captured the first detailed 'molecular movie' showing DNA being unzipped at the atomic level -- revealing how cells begin the crucial process of copying their genetic material.

Mutations in BRCA2—a gene known to repair damaged DNA and suppress tumor formation—can predict an individual's predisposition ...