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新型光学生物传感器 Gαi bONE-GO:精准探测 GPCR 激活 Gαi亚基,改写 ...
为解决常用光学生物传感器测量 GPCR 刺激的 G 蛋白活性时存在的问题,研究人员开发了基于生物发光共振能量转移(BRET)的光学生物传感器 Gα i bONE-GO。该传感器能更灵敏地检测内源性 Gα i 激活,还发现天然阿片神经肽的新特性,意义重大。 G 蛋白偶联受体 ...
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