当疫苗注入手臂的瞬间,身体里正上演着比《饥饿游戏》更残酷的生存竞赛?在名为"生发中心(Germinal ...
Patients with a immunohistochemically defined, germinal-center tumor subtype have an improved outcome compared with patients with the non-germinal-center phenotype when treated with CHOP only ...
A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a ...
Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and ...
New imaging reveals a built-in safeguard that allows B cell populations to rapidly expand in germinal centers without introducing deleterious mutations. Germinal centers are high-speed evolution ...
But recent work suggests that "recall germinal centers"—those formed upon re-exposure—are actually generating a different, second line of defense. By drawing heavily on naive and untrained B ...