文章研究表明，表观药物Panobinostat和Tazemetostat的组合可以通过对肿瘤细胞的组蛋白修饰重编程，抑制与肿瘤进展相关的基因表达。通过HiTIP-seq技术，研究人员对来自DMG患者肿瘤干细胞的表观修饰改变进行了深入分析，揭示了这两种 ...

DelveInsight’s, “Glioma Pipeline Insight, 2025” report provides comprehensive insights about 180+ companies and 200+ pipeline ...

Diffuse midline glioma (DMG), H3K27-altered, is a lethal pediatric high-grade tumor, lacking effective treatment options, ...

The detailed molecular characterization of malignant glioma and medulloblastoma has not only more accurately defined specific subgroupings in individual morphological categories, but has also laid ...

《Acta Neuropathologica Communications》：Curative timed NK cell-based immunochemotherapy aborts brain tumour recurrence driven by mesenchymal glioma stem cells ...

Diffuse intrinsic pontine gliomas (DIPGs) are aggressive pediatric brain tumors found in the pontine region of the brainstem.

An international team of clinical collaborators, led by physician scientists from Dana-Farber Cancer Institute, performed a ...

Glioblastoma multiforme (GBM), commonly referred to as glioblastoma, is a malignant intracranial tumor derived from glial ...

A progress report for a phase 1 trial of CLD-101 in recurrent glioma shows safety and feasibility at multiple intracerebral ...

A study shows that high-grade glioma tumor cells harboring DNA alterations in the gene PDGFRA responded to the drug avapritinib, which is already approved by the United States Food and Drug ...

A recent study published in MedComm – Future Medicine by a research team from Fudan University provides an in-depth ...

The Macon-Bibb community is mourning the loss of a 9-year-old who was diagnosed with a rare brain disease. Kevin Lobello, a ...