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生物通
12 天
SERPINI1:肝细胞癌诊断与预后的新希望
本研究首次证实了 SERPINI1 在 HCC 中的诊断和预后价值,以及它在促进 HCC 细胞增殖、迁移和侵袭中的生物学功能。SERPINI1 在 HCC 患者血清中的水平显著高于健康对照者,且与肿瘤大小、分期、分化程度、血管侵犯和淋巴结转移相关。SERPINI1 与 AFP 联合检测可提高诊断的敏感性和特异性,有望成为 HCC 潜在的诊断和预后生物标志物。
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