Integrin adhesion complexes (IACs) are the main components involved in cell adhesion to the extracellular matrix (ECM) and serve as key sensors of signals coming from the microenvironment. IAC ...

In the present review, we focus on the cellular mechanical response through ECM-integrin-cytoskeleton-nucleus axis and critically discuss the molecular basis of focal adhesion cell mechanosensing. We ...

assemble focal adhesions and display tissue phenotypes characteristic of MECs interacting with a stiff matrix. Such observations underscore the importance of integrin signalling and Rho-dependent ...

Verastem Oncology , a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, announced today multiple oral and poster presentations at the ...

Univ. Lille, Inserm, CHU Lille, U1167─RID-AGE─Risk Factors and Molecular Determinants of Aging-Related Diseases, Institut Pasteur de Lille, F-59000 Lille, France ...

I’m thinking of this as I listen to the new Focal Bathys MG. Building on 2022’s Bathys—an incisive pair of $699 Bluetooth ANC headphones that found immediate success among audiophiles—the ...

Stanford Medicine researchers recently announced promising animal studies involving a hydrogel they developed to prevent post-surgery abdominal adhesions. Abdominal adhesions occur when excessive scar ...

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The cover glasses were first plasma-cleaned by exposure to O 2-plasma for 2 min, making the surface hydrophilic, and allowing better adhesion of cells for microscopy experiments ... Edmund Optics) ...