Transform the verified clones into the cell lines of interest to test their ability to knock down gene expression. The vector(s) may be transiently transfected into any commonly used cell line ...

1 Scientists have harnessed RNAi in the laboratory to selectively silence target gene expression, a technique known as gene knockdown ... 9 Functional genomics researchers now commonly use RNAi to ...

it has been very difficult to just simply drop these ribozymes into messenger RNAs and get them to knock down gene expression.” His one concern is that better inhibitors will be needed ...

Both gene knockout and knock-in models are powerful ... latter of which is associated with superior efficacy in knocking down ...

The technique: A specific short peptide aimed at fat cells can deliver a DNA sequence that knocks down expression of a key fatty acid binding protein ... functions of adipocytes—a notoriously ...

Qure (QURE) announced that the Independent Data Monitoring Committee for EPISOD1, uniQure’s Phase I/II clinical trial of AMT-162, an ...