Transform the verified clones into the cell lines of interest to test their ability to knock down gene expression. The vector(s) may be transiently transfected into any commonly used cell line ...

1 Scientists have harnessed RNAi in the laboratory to selectively silence target gene expression, a technique known as gene knockdown ... 9 Functional genomics researchers now commonly use RNAi to ...

Both gene knockout and knock-in models are powerful ... latter of which is associated with superior efficacy in knocking down ...

The technique: A specific short peptide aimed at fat cells can deliver a DNA sequence that knocks down expression of a key fatty acid binding protein ... functions of adipocytes—a notoriously ...

The firm will use the funds to develop its lead candidate in primary hyperoxaluria type 1 and other pipeline products in liver and CNS disorders.