Serum biochemical indicators, morphological changes, hepatic macrophage markers, as well as macrophage M1/M2 markers were detected. Secondly, macrophage scavenger clodronate liposomes were injected to ...
Tumor-promoting TAMs comprise subpopulations characterized by distinct markers and unique transcriptional profiles ... However, increasing evidence suggests that the polarization state of macrophages ...
The transition of MDMs from M1 to M2 phenotype was evaluated through gene expression and protein synthesis of M2 macrophage markers, namely scavenger receptors (CD163 and CD204), and mannose ...
Bone marrow derived macrophages were prepared and polarised to classic (M1) or alternative (M2) activation states. Markers for macrophage phenotype were measured using quantitative RT-PCR. Results ...
Colorectal cancer (CRC) is the third most common malignancy and the second leading cause of cancer-related deaths worldwide.
M2 macrophages were further classified into M2a, M2b, M2c and M2d subsets. On the surface of M1 macrophages, Toll-like receptor 2/4, CD80, CD86, inducible nitric oxide synthase and MHC II are ...
Interestingly, this study noted an increase in the proportion of M1 macrophages and a decrease in M2 macrophages in CRC, contradicting the M1/M2 polarization theory. Functional analyses suggests ...
The interaction between the microenvironment and cancer cells remains to be further elucidated. In this study, we characterized the prognostic value of P311 in PDAC and aimed to examine the ...
Summary of the Application of M2-PK in EDTA-plasma As compared with the well-established tumor markers, Tumor M2-PK proves to have at least equal sensitivity in pancreatic, gastric, esophageal ...