News Medical on MSN4mon
Study reveals how inflammatory immune cells enhance prostate cancer resistance
Researchers focused particularly on the role of M1 and M2 macrophages in the tumor microenvironment. Macrophages are immune ...
EurekAlert!18d
Lrrk2 promotes M1 macrophage polarization via regulating cytokine (IFN-γ) and TLR4 (LPS)-mediated responses
Mechanistic studies showed that Lrrk2 promotes macrophage polarization toward the M1 phenotype by enhancing STAT1 phosphorylation in response to IFN-γ signaling. This function is dependent on the ...