This paper presents the important finding that BNIP3/NIX, a mitophagy receptor, and its binding to ATG18 are required for mitophagy during muscle cell reorganization in Drosophila. Although the ...

Scientists have identified a potential new benefit of a well-known drug: extending lifespan by improving mitophagy, the ...

Compromised clearance of dysfunctional mitochondria, through the process of mitophagy, has garnered attention as an essential contributor to aging and neurodegeneration. Schmid and colleagues 1 ...

The five-year, $1.8 million grant, "Mechanisms of Mitophagy in Tissue Health and Homeostasis," will be led by Ryan Insolera, Ph.D., assistant professor of ophthalmology, visual and anatomical ...