Plasmacytoid urothelial carcinoma is rare and aggressive, with poor outcomes and challenges in accurate staging. National and institutional data reveal discrepancies in chemotherapy use and disease ...

Cytokines are proteins, peptides or glycoproteins secreted by lymphocytes and monocytes ... and immunological effects of prior vaccination. Plasmacytoid dendritic cells (pDC) are the major IFN ...

Due to the loss of immune tolerance, initiation phase leads to the appearance of autoreactive T lymphocytes, which contribute to the maturation of autoreactive ... neutrophil extracellular trap ...

Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells do not express ...

Another speculation is that the multiclonal lymphocytes may proliferate in a polyclonal fashion until one clone emerges, acquires malignant characteristics and then develops into frank lymphomas.

The kinase IRAK4 promotes endosomal TLR and immune complex signaling in B cells and plasmacytoid dendritic cells.

Neoplastic cell morphology in peripheral blood (A) and bone marrow aspirate films (B) showing small- to medium-sized lymphoplasmacytic lymphocytes (May Grunwald Giemsa stain, 1000×). Bone marrow ...

The long-term safety of ibrutinib was proven in patients with newly diagnosed or relapsed or refractory (R/R) chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). Quality-of ...

A list of facts and trends to know about the current landscape of urologic cancer management and research in the US.

About 23,690 new cases of CLL (14,340 in males and 9,350 in females) About 4,460 deaths from CLL ( 2,810 in males and 1,650 in females) CLL accounts for about 1 in 3 new cases of leukemia in the US, ...

Researchers explore the cellular and molecular adaptations associated with human secondary lymphoid tissue in adults during ...