The phase 3 trial design evaluating IMNN-001 in newly diagnosed advanced ovarian cancer has been finalized among regulatory ...

First and only immunotherapy to show meaningful overall survival benefit in a Phase 2 trial in patients with advanced ovarian cancer. Initiation of trial sites underway for ground ...

Transgenic animals continue to play an essential role in many aspects of zebrafish research, including the development of disease models. The most widely used system for zebrafish transgenesis is the ...

Illustrator is widely regarded as the gold standard for vector graphic design. Whether you’re a seasoned professional or a beginner stepping into the world of digital art, this software provides all ...

Plasmid-mediated dissemination of antibiotic resistance among fecal Enterobacteriaceae in natural ecosystems may contribute to the persistence of antibiotic resistance genes in anthropogenically ...

School of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, P.R. China School of Chemical & Material Engineering, Jiangnan University, Wuxi 214122, P.R. China ...

In one system, plasmid DNA was tethered to a surface ... a similar approach could be equally beneficial to the design of DNA-delivery-vector libraries 101,102. It is an exciting time for the ...

Each sgRNA sequence was cloned into a sgRNA expression vector with a modified mouse U6 promoter from the pMJ179 plasmid (cat no. 85996, Addgene). A total of 1 d before transfection, 1.5 × 10 4 HEK293T ...

Finally, we reasoned that certain resistance plasmids should themselves expedite re-seeding-transfer-invasion cycles within the infected host. In particular, this should pertain to plasmid-encoded ...