Prion Disease is currently an invariably fatal condition without treatment or cure. Despite multiple prior treatment studies, including quinacrine, doxycycline, and pentosan polysulfate, no ...

Mayo Clinic launched a new prion test, RT-QuIC Prion, CSF, which can distinguish prion disease from other causes of rapidly ...

Jan. 14, 2025 — Researchers have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition.

The development of treatment strategies will rely on results from two main areas: (i) efforts to identify infected but asymptomatic individuals, and (ii) research to understand prion biology ...

They now run a lab at the Broad Institute in Boston. By 2024 they had created an editor that, in mice, turns off the prion ...

In TSEs the normal cellular prion protein (PrP C) is transformed into an infectious disease-associated isoform, PrP Sc — a potential target for immunotherapy. In the March 6 Nature, Anthony R. White ...

Prion diseases are characterized by abnormal folding of the host’s naturally-occurring ... such as alleviating suffering by improving the understanding, prevention, and treatment of illnesses. “She ...

The National Prion Disease Pathology Surveillance Center (NPDPSC) is the only Center of its kind in the U.S., which coordinates autopsies and neuropathologic examinations of suspected prion disease ...