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Variant screening 助力长效且高选择性 PYY3–36类似物开发,为肥胖与糖尿 ...
为解决肽 YY(PYY 3–36 )半衰期短、选择性欠佳影响其临床应用的问题,研究人员开展了 PYY 3–36 变体筛选研究。他们获得高选择性长效类似物,联合 GLP-1 类似物效果更佳,为优化 PYY 的临床应用提供依据。
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