Both the lipid and protein composition of the endosome changes along the pathway to lysosomes (Box 1). Figure 1: A schematic of the ESCRT machinery involved in sorting cargo to lysosomes via MVBs.

Endosomes are primarily intracellular sorting organelles ... However, these activated receptors also signal from endosome membranes, where they can physically interact with some of their ...

Endosomes act as "sorting stations" inside cells ... which plays a vital role in regulating endosome maturation. This gene encodes a deubiquitinating enzyme that removes ubiquitin tags from ...