近日收到了一份来自无锡医学院老师的采购订单,老师咨询人原钙黏素1(PCDH1)、组织型纤溶酶原激活因子(tPA)、总抗氧化状态(TOS)、人白介素2受体(IL-2R)、转铁蛋白受体1(TFR1)ELISA试剂盒、转化生长因子-β1(TGF-β1)等指标试剂盒,通过对样本,样本量,样本指标沟通后 ...
Males with pulmonary arterial hypertension (PAH) have more proinflammatory macrophages — a type of immune cell — in the lungs than do females with the disease, a study suggests. Researchers identified ...
“We developed a potent TNF-alpha inhibitor antibody to be used to treat Alzheimer’s and, since this antibody cannot cross the blood-brain barrier by itself, we combined it with our NewroBus TM ...
This important study reveals that disrupting fatty acid metabolism in macrophages significantly restricts the growth of Mycobacterium tuberculosis, showing that impaired lipid processing triggers ...
Our findings revealed that EGCG inhibited NEDD8, thus stabilizing HUWE1, a crucial E3 ubiquitin ligase involved in protein degradation. HUWE1 binds and degrades TFR1, a protein essential for cellular ...
When exposed to various stimuli, monocytes/macrophages are recruited to and retained within the local tissue microenvironment, where they can activate and display either proinflammatory or ...
其次通过Western Blot检测TfR1-FPN1的蛋白含量实验,ICP-MS定量分析细胞内铁含量实验和转录组测序实验,进一步验证GaSₓ具有干扰铁代谢的潜力。 Figure 2. GaSx disrupted tumor cell iron metabolism. (a)Confocal images of CT26 cell endocytosis after GaSx ...
Results from the Real-World IMPaCT Study The FORCE™ Platform Achieves Robust and Durable DUX4 Suppression and Improves Muscle Function in Facioscapulohumeral Muscular Dystrophy Mouse Model The FORCE™ ...